Journal article
Testicular volume and clinical correlates of hypothalamic-pituitary-testicular function: A cross-sectional study in obese men
M Tang Fui, R Hoermann, G Wittert, M Grossmann
Asian Journal of Andrology | WOLTERS KLUWER MEDKNOW PUBLICATIONS | Published : 2020
Open access
Abstract
The aim of this study was to determine whether testicular volume is correlated with clinical and biochemical markers of hypothalamic-pituitary-testicular (HPT) axis function. This was a cross-sectional substudy of a larger randomized controlled trial including obese men, body mass index (BMI) ≥30 kg m-2, with a total testosterone level <12 nmol l-1. Testicular volume was measured by orchidometer, testosterone by liquid chromatography/tandem mass spectrometry, and body composition by dual-energy X-ray absorptiometry. Men completed the Aging Males' Symptoms (AMS) score, International Index of Erectile Function-5 (IIEF-5), physical function, and handgrip dynamometer testing. Eighty-nine men par..
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Awarded by National Health and Medical Research Council
Funding Acknowledgements
MNTF was supported an ESA-RACP research establishment fellowship and MG by a career Development Fellow (1024139) from the NHMRC. Bayer Pharma AG (Berlin, Germany) provided testosterone, placebo and financial support to conduct investigation during the RCT phase. Bayer Pharma AG had no role in trial design, data analysis or writing the manuscript.